Published by admin on Friday, January 3, 2020


After breast cancer operations a quarter to a half of people will continue to have some degree of chronic pain at the site of surgery for 3 months or longer. For most of these people the pain will be mild, but in some it can be moderate or severe.

We are therefore interested in finding medications that can be administered around the time of surgery to prevent the development or reduce the severity of chronic pain.

Lidocaine infusions have already been tested in 4 small studies of patients undergoing breast cancer surgery, and appear to be safe and effective at reducing chronic pain rates.

However, small studies can be misleading and larger studies conducted to a very high standard are required before lidocaine infusions can be recommended as routine for breast cancer or other types of surgery.

This study will assess whether lidocaine is effective for breast cancer surgery. It will also assess how practical it will be to conduct a large international trial in patients having a wide variety of surgery.

Participants must be aged between 18 and 79 years, and be scheduled to have elective breast cancer surgery.

If you are interested in taking part please read this Patient Information Sheet.


The study was recently featured in an article by The West Australian


The ANZCA Bulletin

Journal of Pain – editorial

Journal of Pain – review article

The LOLIPOP study is funded by a grant from the Australian and New Zealand College of Anaesthetists